HTRA1 inhibitor 17

Chemical Structure : HTRA1 inhibitor 17

加入收藏

货号: PC-22463Not For Human Use, Lab Use Only.

HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM.
HTRA1 inhibitor 17 only weakly inhibits chymotrypsin, kallikrein 7, caspase 6 and caspase 9 in a panel of 35 proteases.

物理化学性质&存储条件

分子量	583.96
分子式	C31H43BClN3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((R)-((S)-2-((S)-3-(3-chlorophenyl)-2-(2,2-dimethyl-3-phenylpropanamido)propanamido)-4-methylpentanamido)(cyclobutyl)methyl)boronic acid

参考文献

1. Dennis DG, et al. Bioorg Med Chem Lett. 2024 May 28:129814.