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首页-小分子抑制剂&激动剂-Others-Other Targets-HQY436
HQY436

Chemical Structure : HQY436

CAS No.:

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HQY436 (HQY 436)

货号: PC-21417Not For Human Use, Lab Use Only.

HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

HQY436 is a specific, orally bioavailable inhibitor of pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3) with binding IC50 of 0.15 uM, exhibits potent antitumor activity.

物理化学性质&存储条件

分子量 407.28
分子式 C22H26BN3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-(4-acetylpiperazin-1-yl)phenyl)-3-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)propanamide

参考文献

1. Shen P, et al. Sci Adv. 2023 Nov 24;9(47):eadj0123.

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