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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-HN252
HN252

Chemical Structure : HN252

CAS No.:

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HN252 (HN 252, HN-252)

货号: PC-20365Not For Human Use, Lab Use Only.

HN252 is a potent protein phosphatase 1B (PPM1B) inhibitor with Ki of 0.52 uM and IC50 of 0.76 uM, shows no inhibition against topoisomerases in vitro.

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纯度 & COA & 质检文件 纯度: 99.9% (HPLC) Select Batch:

生物&药学活性

HN252 is a potent protein phosphatase 1B (PPM1B) inhibitor with Ki of 0.52 uM and IC50 of 0.76 uM, shows no inhibition against topoisomerases in vitro.

物理化学性质&存储条件

分子量 321.33
分子式 C19H15NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-amino-3'',4''-dihydroxy-[1,1':4',1''-terphenyl]-4-carboxylic acid

参考文献

1. Zhiyuan Lu, et al. J Cell Mol Med. 2020 Nov;24(22):13463-13471.

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