HLI373 dihydrochloride | Hdm2 inhibitor | Probechem Biochemicals

Chemical Structure : HLI373 dihydrochloride

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HLI373 dihydrochloride (HLI-373 dihydrochloride)

货号: PC-28721Not For Human Use, Lab Use Only.

HLI373 dihydrochloride is a small molecule ubiquitin ligase (E3) Hdm2 inhibitor, stabilizes Hdm2 and p53, activating p53-dependent transcription, and inducing cell death, induces apoptosis of tumor cells lines that is sensitive to DNA-damaging agents.

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100 mg		Get quote

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生物&药学活性

HLI373 dihydrochloride is a small molecule ubiquitin ligase (E3) Hdm2 inhibitor, stabilizes Hdm2 and p53, activating p53-dependent transcription, and inducing cell death, induces apoptosis of tumor cells lines that is sensitive to DNA-damaging agents.

物理化学性质&存储条件

分子量	414.33
分子式	C18H25Cl2N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((3-(dimethylamino)propyl)amino)-3,10-dimethylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione dihydrochloride

参考文献

1. Kitagaki J, et al. Mol Cancer Ther. 2008 Aug;7(8):2445-54.

HLI373 dihydrochloride (HLI-373 dihydrochloride)

生物&药学活性

物理化学性质&存储条件

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HLI373 dihydrochloride (HLI-373 dihydrochloride)

生物&药学活性

物理化学性质&存储条件

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