HIV capsid modulator 5-33d

Chemical Structure : HIV capsid modulator 5-33d

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货号: PC-27767Not For Human Use, Lab Use Only.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

HIV capsid modulator 5-33d is a potent HIV capsid modulator, exhibits potent antiviral activity with EC50 of 0.14 uM, exhibits potent binding affinities to the CA hexamer with KD of 59.0 nM, but not CA monomer.
5-33d exerts dual-stage inhibition by disrupting CA-host binding and modulating capsid assembly.

物理化学性质&存储条件

分子量	684.75
分子式	C32H31F3N6O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(1-(5-((2-(cyclopropanesulfonamido)ethyl)thio)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)-2-(3,5-difluorophenyl)ethyl)-2-(5-fluoro-1H-indol-3-yl)acetamide

参考文献

1. Jiang X, et al. J Med Chem. 2026 Aug 13;69(15):18783-18799.