HIF2α inhibitor Compound-c2

Chemical Structure : HIF2α inhibitor Compound-c2

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货号: PC-25968Not For Human Use, Lab Use Only.

HIF2α inhibitor Compound-c2 is a selective HIF2α inhibitor that binds to the PAS-B domain of HIF2α, disrupts the interaction between HIF2α and the molecular chaperone Hsp70, leading to proteasomal degradation of HIF2α and the induction of apoptosis in ccRCC.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	311.32
分子式	C17H14FN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-N-(3-ethyl-2-oxo-2,3-dihydroquinazolin-4(1H)-ylidene)-4-fluorobenzamide

参考文献

1. Heritz JA, et al. Commun Med (Lond). 2026 Jan 12. doi: 10.1038/s43856-025-01356-x.

2. Patent WO2025091029 A1.