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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase-HIF2α-IN-1
HIF2α-IN-1

Chemical Structure : HIF2α-IN-1

CAS No.: 1799948-06-3

HIF2α-IN-1

货号: PC-45759Not For Human Use, Lab Use Only.

A potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay. .

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10 mg ¥8000 In stock
25 mg ¥16800 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent HIF-2α inhibitor with IC50 of <500 nM in HIF-2α scintillation proximity assay.

物理化学性质&存储条件

分子量 405.2961
分子式 C16H8F5NO4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzonitrile, 3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-2,3-dihydro-3-hydroxy-1,1-dioxidobenzo[b]thien-5-yl]oxy]-5-fluoro-

参考文献

1. Bruick Richard Keith, et al. From PCT Int. Appl. (2016), WO 2016057242 A1 20160414.

2. Dixon Darryl David, et al. From PCT Int. Appl. (2015), WO 2015095048 A1 20150625.

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