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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase-HIF-PH inhibitor DMOG
HIF-PH inhibitor DMOG

Chemical Structure : HIF-PH inhibitor DMOG

CAS No.: 89464-63-1

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HIF-PH inhibitor DMOG (Dimethyloxallyl Glycine)

货号: PC-22692Not For Human Use, Lab Use Only.

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF prolyl hydroxylase (HIF-PH), induces HIF-1α stabilisation and accmulation in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF prolyl hydroxylase (HIF-PH), induces HIF-1α stabilisation and accmulation in vitro and in vivo.

物理化学性质&存储条件

分子量 175.14
分子式 C6H9NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Methyl 2-((2-methoxy-2-oxoethyl)amino)-2-oxoacetate

参考文献

1. Sun T, et al. J Oncol. 2021 Dec 3;2021:9958483.

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