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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Topoisomerase-HH-N25
HH-N25

Chemical Structure : HH-N25

CAS No.: 1643807-17-3

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HH-N25 (HH N25)

货号: PC-72675Not For Human Use, Lab Use Only.

HH-N25 is a a potent and selective topoisomerase I (TOP1) inhibitor with potent antiproliferative activities against a panel of human breast cancer cell lines (IC50=0.045-4.2 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    HH-N25 is a a potent and selective topoisomerase I (TOP1) inhibitor with potent antiproliferative activities against a panel of human breast cancer cell lines (IC50=0.045-4.2 uM).
    HH-N25 shows potent antitumor activities in human breast cancer cells in vitro and in vivo.

    物理化学性质&存储条件

    分子量 402.896
    分子式 C23H15ClN2OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(benzylamino)-10-chloro-12H-thiochromeno[2,3-c]quinolin-12-one

    参考文献

    1. Bashir Lawal, et al. J Inflamm Res. 2021 Sep 22;14:4901-4913.

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