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首页-小分子抑制剂&激动剂-Tyrosine Kinase-c-Fes Kinase-HG-7-27-01
HG-7-27-01

Chemical Structure : HG-7-27-01

CAS No.: 1135270-45-9

HG-7-27-01 (c-Fes inhibitor)

货号: PC-61639Not For Human Use, Lab Use Only.

HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases.

    物理化学性质&存储条件

    分子量 700.815
    分子式 C37H43F3N10O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(1E)-2-[5-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-2-pyrazinyl]ethenyl]-

    参考文献

    1. Hellwig S, et al. Chem Biol. 2012 Apr 20;19(4):529-40.

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