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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -HDGFRP2 PWWP domain inhibitor BBP
HDGFRP2 PWWP domain inhibitor BBP

Chemical Structure : HDGFRP2 PWWP domain inhibitor BBP

CAS No.: 166196-54-9

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HDGFRP2 PWWP domain inhibitor BBP

货号: PC-22774Not For Human Use, Lab Use Only.

BBP is a small molecule inhibitor of the hepatoma-derived growth factor-related protein 2 (HDGFRP2) PWWP domain, dually targets both HDGFRP2 and PSIP1 PWWP domains, engage with the aromatic cage of the HDGFRP2 PWWP domain.

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10 mg ￥1280 In stock
25 mg ￥1980 In stock
50 mg ￥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BBP is a small molecule inhibitor of the hepatoma-derived growth factor-related protein 2 (HDGFRP2) PWWP domain, dually targets both HDGFRP2 and PSIP1 PWWP domains, engage with the aromatic cage of the HDGFRP2 PWWP domain.
The PWWP domain of hepatoma-derived growth factor-related protein 2 (HDGFRP2) recognizes methylated histones to initiate the recruitment of homologous recombination repair proteins to damaged silent genes.

物理化学性质&存储条件

分子量 224.06
分子式 C8H6BrN3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(4-bromo-1H-pyrazol-3-yl) pyridine

参考文献

1. Wei X, et al. FEBS Lett. 2024 Jul 19. doi: 10.1002/1873-3468.14981.

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