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HDAC6 inhibitor 4e

Chemical Structure : HDAC6 inhibitor 4e

CAS No.: 1648893-34-8

HDAC6 inhibitor 4e

货号: PC-27053Not For Human Use, Lab Use Only.

HDAC6 inhibitor 4e is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.7 nM, shows 355-fold selectivity over HDAC1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

HDAC6 inhibitor 4e is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.7 nM, shows 355-fold selectivity over HDAC1.

物理化学性质&存储条件

分子量 384.48
分子式 C21H28N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((1-butyl-3-(3-(dimethylamino)phenyl)ureido)methyl)-N-hydroxybenzamide

参考文献

1. Tavares MT, et al. ACS Med Chem Lett. 2017 Sep 5;8(10):1031-1036.

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