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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-HAR-171
HAR-171

Chemical Structure : HAR-171

CAS No.: 1349902-37-9

HAR-171 (HAR171)

货号: PC-62899Not For Human Use, Lab Use Only.

HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).

    物理化学性质&存储条件

    分子量 417.978
    分子式 C23H32ClN3O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N1-(4-chlorophenyl)-N2-(7-azadispiro[5.1.58.36]hexadecan-15-yl)oxalamide

    参考文献

    1. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.

    2. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6.

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