H3B-960 | WRN helicase inhibitor | Probechem Biochemicals

Chemical Structure : H3B-960

CAS No.: 2912294-89-2

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货号: PC-21005Not For Human Use, Lab Use Only.

H3B-960 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 60 nM.

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H3B-960 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 60 nM.

分子量	534.43
分子式	C21H16F6N4O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(p-tolyl)-2-((4-(4-(trifluoromethoxy)phenyl)-6-(trifluoromethyl)pyrimidine)-2-sulfonamido)acetamide

1. Mackenzie J Parker, et al. Biochemistry. 2023 Jul 18;62(14):2147-2160.