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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-H210
H210

Chemical Structure : H210

CAS No.:

H210 (dual Mdm2/MdmX inhibitor H210)

货号: PC-38075Not For Human Use, Lab Use Only.

H210 is a potent dual Mdm2/MdmX inhibitor with Ki of 9.66/2.89 nM, respectively..

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

H210 is a potent dual Mdm2/MdmX inhibitor with Ki of 9.66/2.89 nM, respectively.

物理化学性质&存储条件

分子量 575.874
分子式 C30H21Cl3N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-((4S,5R)-5-(4-chlorophenyl)-4-(3,5-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-yl)-1-phenyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione

参考文献

1. Xiyao Cheng, et al. Nat Commun. 2022 Feb 28;13(1):1087.

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