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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-Guangxitoxin 1E
Guangxitoxin 1E

Chemical Structure : Guangxitoxin 1E

CAS No.: 1233152-82-3

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Guangxitoxin 1E

货号: PC-21704Not For Human Use, Lab Use Only.

Guangxitoxin 1E is a potent, specific inhibitor of Kv2.1 (KCNB1) and Kv2.2 with IC50 of 1-3 nM, has no significant effect on KV1.2, KV1.3, KV1.5, KV3.2 and BK potassium channels, also inactive against calcium and sodium channels CaV1.2, CaV2.2, NaV1.5, NaV1.7, NaV1.8.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Guangxitoxin 1E is a potent, specific inhibitor of Kv2.1 (KCNB1) and Kv2.2 with IC50 of 1-3 nM, has no significant effect on KV1.2, KV1.3, KV1.5, KV3.2 and BK potassium channels, also inactive against calcium and sodium channels CaV1.2, CaV2.2, NaV1.5, NaV1.7, NaV1.8.

物理化学性质&存储条件

分子量 3948.6
分子式 C178H248N44O45S7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

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