Chemical Structure : Guanabenz
CAS No.: 5051-62-7
货号: PC-62319Not For Human Use, Lab Use Only.
Guanabenz (WY 8678) is an α2 adrenergic receptor agonist that is used as an antihypertensive agent, also has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex.
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Guanabenz (WY 8678) is an α2 adrenergic receptor agonist that is used as an antihypertensive agent, also has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex.
Guanabenz also has antiparasitic activity against replicative stages of Toxoplasma.
分子量 | 231.08 | |
分子式 | C8H8Cl2N4 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine |
1. Das I, et al. Science. 2015 Apr 10;348(6231):239-42.
2. Crespillo-Casado A, et al. Elife. 2017 Apr 27;6. pii: e26109.
3. Benmerzouga I, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6939-45.
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