GpTx-1 |CAS:1661050-12-9 Probechem Biochemicals

Chemical Structure : GpTx-1

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GpTx-1 (GpTx1)

货号: PC-63263Not For Human Use, Lab Use Only.

GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5..

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生物&药学活性

GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5.

物理化学性质&存储条件

分子量
分子式	C176H271N53O45S7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	H-Asp-Cys-Leu-Gly-Phe-Met-Arg-Lys-Cys-Ile-Pro-Asp-Asn-Asp-Lys-Cys-Cys-Arg-Pro-Asn-Leu-Val-Cys-Ser-Arg-Thr-His-Lys-Trp-Cys-Lys-Tyr-Val-Phe-NH2

参考文献

1. Murray JK, et al. J Med Chem. 2015 Mar 12;58(5):2299-314.

2. Deuis JR, et al. Toxins (Basel). 2016 Mar 17;8(3). pii: E78.

3. Biswas K, et al. ACS Chem Biol. 2017 Sep 15;12(9):2427-2435.

GpTx-1 (GpTx1)

生物&药学活性

物理化学性质&存储条件

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GpTx-1 (GpTx1)

生物&药学活性

物理化学性质&存储条件

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