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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-Govorestat
Govorestat

Chemical Structure : Govorestat

CAS No.: 2170729-29-8

Govorestat (AT-007, AT007)

货号: PC-38679Not For Human Use, Lab Use Only.

Govorestat (AT-007) is a potent, selective, CNS-penetrant aldose reductase (aldehyde reductase) inhibitor with IC50 of 0.1 nM, reduces toxic galactitol levels and prevents galactosemia disease complications in vivo.

规格 价格 库存 数量
5 mg ¥1280 In stock
10 mg ¥1980 In stock
25 mg ¥3480 In stock
50 mg ¥5580 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Govorestat (AT-007) is a potent, selective, CNS-penetrant aldose reductase (aldehyde reductase) inhibitor with IC50 of 0.1 nM, reduces toxic galactitol levels and prevents galactosemia disease complications in vivo.

物理化学性质&存储条件

分子量 425.41
分子式 C17H10F3N3O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]thieno[3,4-d]pyridazine-1-acetic acid

参考文献

1. Bhooshan N, et al. Lung Cancer. 2016 Nov;101:88-91.

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