Govorestat (AT-007) | Aldose Reductase inhibitor | Probechem Biochemicals

Chemical Structure : Govorestat

CAS No.: 2170729-29-8

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Govorestat (AT-007, AT007)

货号: PC-38679Not For Human Use, Lab Use Only.

Govorestat (AT-007) is a potent, selective, CNS-penetrant aldose reductase (aldehyde reductase) inhibitor with IC50 of 0.1 nM, reduces toxic galactitol levels and prevents galactosemia disease complications in vivo.

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5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
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100 mg		Get quote

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生物&药学活性

Govorestat (AT-007) is a potent, selective, CNS-penetrant aldose reductase (aldehyde reductase) inhibitor with IC50 of 0.1 nM, reduces toxic galactitol levels and prevents galactosemia disease complications in vivo.

物理化学性质&存储条件

分子量	425.41
分子式	C17H10F3N3O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4-Dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]thieno[3,4-d]pyridazine-1-acetic acid

参考文献

1. Bhooshan N, et al. Lung Cancer. 2016 Nov;101:88-91.

Govorestat (AT-007, AT007)

生物&药学活性

物理化学性质&存储条件

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Govorestat (AT-007, AT007)

生物&药学活性

物理化学性质&存储条件

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