Gossypetin

Chemical Structure : Gossypetin

CAS No.: 489-35-0

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货号: PC-28335Not For Human Use, Lab Use Only.

Gossypetin is a hexahydroxylated flavonoid within antioxidant, antibacterial and anticancer activities, is a potent inhibitor of MKK3 and MKK6, also is a USP5-Cav3.2 disruptor.

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5 mg	￥3280	In stock
10 mg	￥5280	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Gossypetin is a hexahydroxylated flavonoid within antioxidant, antibacterial and anticancer activities, is a potent inhibitor of MKK3 and MKK6, also is a USP5-Cav3.2 disruptor.
Gossypetin ameliorates ionizing radiation-induced oxidative stress in mice liver
Gossypetin reverses inflammatory and neuropathic pain.
Gossypetin induces G2 phase arrest and apoptosis of esophageal cancer cells.
Gossypetin suppresses esophageal cancer growth in vitro and in vivo.

物理化学性质&存储条件

分子量	318.24
分子式	C15H10O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-chromen-4-one

参考文献

1. Rankin SM, et al. Biochem Pharmacol. 1993 Jan 7;45(1):67-75.

2. Khan A, et al. Free Radic Res. 2015 Oct;49(10):1173-86.

3. Gadotti VM, et al. Mol Pain. 2015 Mar 14;11:12.

4. Xie X, et al. Cancer Lett. 2019 Feb 1;442:126-136.

Gossypetin

生物&药学活性

物理化学性质&存储条件

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Gossypetin

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