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首页-小分子抑制剂&激动剂-TGF-beta/Smad-PKC-Go 6983
Go 6983

Chemical Structure : Go 6983

CAS No.: 133053-19-7

Go 6983 (Gö 6983, Goe 6983)

货号: PC-21446Not For Human Use, Lab Use Only.

Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Go 6983 is a potent, pan-PKC inhibitor with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM against PKCα, PKCβ, PKCγ, PKCδ and PKCζ, respectively.

物理化学性质&存储条件

分子量 442.52
分子式 C26H26N4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1-(3-(Dimethylamino)propyl)-5-methoxy-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

参考文献

1. Gschwendt M, et al. FEBS Lett, 1996, 392(2), 77-80.

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