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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-GlyH-101
GlyH-101

Chemical Structure : GlyH-101

CAS No.: 328541-79-3

GlyH-101 (GlyH 101, GlyH101)

货号: PC-45455Not For Human Use, Lab Use Only.

GlyH-101 is a potent CFTR inhibitor with Ki of 4.3 uM.

规格 价格 库存 数量
5 mg ¥880 In stock
10 mg ¥1280 In stock
25 mg ¥2180 In stock
50 mg ¥3580 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GlyH-101 is a potent CFTR inhibitor with Ki of 4.3 uM.
GlyH-101 rapidly and reversibly inhibited forskolin-induced hyperpolarization in nasal potential differences in mice.
GlyH-101 effectively reduces cholera toxin-induced intestinal fluid secretion in a closed-loop model of cholera.

物理化学性质&存储条件

分子量 493.1487
分子式 C19H15Br2N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 58 mg/mL

Chemical Name/SMILES

Glycine, N-2-naphthalenyl-, 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide

参考文献

1. Muanprasat C, et al. J Gen Physiol. 2004 Aug;124(2):125-37.

2. Norimatsu Y, et al. Mol Pharmacol. 2012 Dec;82(6):1042-55.

3. Barman PP, et al. Biochem Biophys Res Commun. 2011 Apr 29;408(1):12-7.

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