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首页-抗体和重组蛋白-Biosimilar Antibody-Glofitamab
Glofitamab

Chemical Structure : Glofitamab

CAS No.: 2229047-91-8

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Glofitamab (Anti-human CD20 mAb, human IgG1-Kappa; RG-6026)

货号: PC-Ab1034Not For Human Use, Lab Use Only.

Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells a CD20/CD3 antibody (comprising two Fab regions for CD20 and one Fab region for CD3). Glofitamab redirects T cells to engage and eliminate malignant B cells..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells a CD20/CD3 antibody (comprising two Fab regions for CD20 and one Fab region for CD3). Glofitamab redirects T cells to engage and eliminate malignant B cells.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Glofitamab; RO 7082859; RG-6026; RG6026; CD20/CD3 TCB 2; CD20/CD3 TCBs; Anti-CD20 CD3 TCB; Anti-CD20/CD3 bispecific monoclonal antibody; CD20-TCB; 2229047-91-8

参考文献

1. 1, Hutchings M, et al. J Clin Oncol. 2021 Jun 20;39(18):1959-1970. 2, Surowka M, et al. MAbs. 2021 Jan-Dec;13(1):1967714. 3, Cremasco F, et al. PLoS One. 2021 Jan 6;16(1):e0241091. 4, Leuk Lymphoma. euk Lymphoma. 2021 Jul 15:1-11.

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