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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-Glabridin
Glabridin

Chemical Structure : Glabridin

CAS No.: 59870-68-7

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Glabridin

货号: PC-24240Not For Human Use, Lab Use Only.

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities.

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10 mg ￥480 In stock
50 mg ￥980 In stock
100 mg ￥1480 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ with EC50 of 6.1 uM, inhibits NADPH oxidase-induced cell-mediated oxidation, exhibits antioxidant, anti-bacterial, antitumor and anti-inflammatory activities.

物理化学性质&存储条件

分子量 324.38
分子式 C20H20O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-4-(8,8-Dimethyl-2,3,4,8-tetrahydropyrano[2,3-f]chromen-3-yl)benzene-1,3-diol

参考文献

1. Rebhun JF, et al. Fitoterapia. 2015 Oct;106:55-61.

2. Tamir S, et al. Cancer Res. 2000 Oct 15;60(20):5704-9.

3. Rosenblat M, et al. J Biol Chem. 1999 May 14;274(20):13790-9.

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