Chemical Structure : Girentuximab
CAS No.: 916138-87-9
货号: PC-Ab1117Not For Human Use, Lab Use Only.
Girentuximab (G250) is a monoclonal antibody (mAb) for targeting CA IX, a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). Carbonic anhydrase IX (CA IX) is the most widely expressed gene in response to hypoxia. Its crucial role in intracellular pH maintenance represents the means by which cancer cells adapt to the toxic conditions of the extracellular milieu..
规格 | 价格 | 库存 | 数量 |
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1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Girentuximab (G250) is a monoclonal antibody (mAb) for targeting CA IX, a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). Carbonic anhydrase IX (CA IX) is the most widely expressed gene in response to hypoxia. Its crucial role in intracellular pH maintenance represents the means by which cancer cells adapt to the toxic conditions of the extracellular milieu.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Girentuximab; Chimeric-monoclonal-antibody-G250; Monoclonal antibody G250; Rencarex; WX-G250; 916138-87-9; Anti-human Carbonic anhydrase IX; Anti-human CA IX; carbonic anhydrase 9 |
1. 1, Chamie K, et al. JAMA Oncol. 2017 Jul 1;3(7):913-920. 2, Hekman MCH, et al. Eur Urol. 2018 Sep;74(3):257-260. 3, Déas O, et al. Hum Gene Ther. 2002 Jun 10;13(9):1101-14. 4, Bleumer I, et al. Br J Cancer. 2004 Mar 8;90(5):985-90.
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