Gemnelatinib (GST-HG161)

Chemical Structure : Gemnelatinib

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货号: PC-38395Not For Human Use, Lab Use Only.

Gemnelatinib (GST-HG161) is a potent and highly selective, orally bioavailable c-Met inhibitor, displays significant antitumor activity in preclinical models, has the potential to be effective in HCC with active c-Met signaling.

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100 mg		Get quote

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生物&药学活性

Gemnelatinib (GST-HG161) is a potent and highly selective, orally bioavailable c-Met (HFGR) inhibitor, displays significant antitumor activity in preclinical models, has the potential to be effective in HCC with active c-Met signaling.

物理化学性质&存储条件

分子量	524.600
分子式	C30H29FN6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-5'-fluoro-1'-(1-(3-(5-((1-methylpiperidin-4-yl)methoxy)pyrimidin-2-yl)phenyl)ethyl)-6'-oxo-1',6'-dihydro-[2,3'-bipyridine]-4-carbonitrile

参考文献

1. Jin Li, et al. 2020 ASCO Annual Meeting I.