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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-Gemcitabine
Gemcitabine

Chemical Structure : Gemcitabine

CAS No.: 95058-81-4

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Gemcitabine (LY 188011;NSC 613327;LY188011;LY-188011)

货号: PC-45149Not For Human Use, Lab Use Only.

Gemcitabine (NSC 613327, LY188011) is a synthetic pyrimidine nucleoside prodrug that works by ihibiting the enzyme ribonucleotide reductase (RNR) and blocking the creation of new DNA.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Gemcitabine (NSC 613327, LY188011) is a synthetic pyrimidine nucleoside prodrug that works by ihibiting the enzyme ribonucleotide reductase (RNR) and blocking the creation of new DNA.
Gemcitabine is a chemotherapy agent for treatment of a number of types of cancer.

物理化学性质&存储条件

分子量 263.1982
分子式 C9H11F2N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Cytidine, 2'-deoxy-2',2'-difluoro-

参考文献

1. Wang H, et al. Anticancer Res. 2011 Oct;31(10):3171-80.

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