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首页-抗体和重组蛋白-Biosimilar Antibody-Galcanezumab
Galcanezumab

Chemical Structure : Galcanezumab

CAS No.: 1578199-75-3

Galcanezumab (Anti-human CGRP mAb, human IgG4P LALA-Kappa; LY 2951742)

货号: PC-Ab1048Not For Human Use, Lab Use Only.

Galcanezumab (LY2951742) is a humanized monoclonal antibody that selectively binds to and blocks the physiologic activity of CGRP. The FDA approved galcanezumab as a once-monthly subcutaneous injection for the preventive treatment of migraine in adults..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Galcanezumab (LY2951742) is a humanized monoclonal antibody that selectively binds to and blocks the physiologic activity of CGRP. The FDA approved galcanezumab as a once-monthly subcutaneous injection for the preventive treatment of migraine in adults.

物理化学性质&存储条件

分子量
分子式 Human IgG4P LALA-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Galcanezumab; Emgality; galcanezumab-gnlm; LY 2951742; LY2951742; calcitonin gene–related peptide; anti-CGRP.

参考文献

1. 1, Detke HC, et al. Neurology. 2018 Dec 11;91(24):e2211-e2221. 2, Gklinos P, et al. Ther Adv Neurol Disord. 2020 Apr 28;13:1756286420918088. 3, Goadsby PJ, et al. N Engl J Med. 2019 Jul 11;381(2):132-141. 4, Martin V, et al. Adv Ther. 2020 May;37(5):2034-2049.

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