GaMF1 |CAS:923689-76-3 Probechem Biochemicals

Chemical Structure : GaMF1

加入收藏

GaMF1 (F1FO-ATP synthase inhibitor)

货号: PC-38231Not For Human Use, Lab Use Only.

GaMF1 is a novel antimycobacterial compound that targets the F1FO-ATP synthase γ subunit loop.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GaMF1 is a novel antimycobacterial compound that targets the F1FO-ATP synthase γ subunit loop.
GaMF1 is bactericidal and is active against multidrug- as well as bedaquiline-resistant strains.
Combining GaMF1 with bedaquiline or novel diarylquinoline analogues showed potentiation without inducing genotoxicity or phenotypic changes in a human embryonic stem cell reporter assay.
GaMF1 presents an attractive lead for the discovery of a novel class of anti-tuberculosis F-ATP synthase inhibitors.

物理化学性质&存储条件

分子量	426.318
分子式	C20H20BrN5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-bromo-N-(4-((4-(ethylamino)-6-methylpyrimidin-2-yl)amino)phenyl)benzamide

参考文献

1. Adam Hotra, et al. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13295-13304.

GaMF1 (F1FO-ATP synthase inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GaMF1 (F1FO-ATP synthase inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.