GW 841819X |CAS:146135-18-4 Probechem Biochemicals

Chemical Structure : GW 841819X

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GW 841819X (GW841819X)

货号: PC-62317Not For Human Use, Lab Use Only.

GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain that displays activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia..

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生物&药学活性

GW 841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomain that displays activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia.

物理化学性质&存储条件

分子量	487.94
分子式	C26H22ClN5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-benzyl (6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)carbamate

参考文献

1. Chung CW, et al. J Med Chem. 2011 Jun 9;54(11):3827-38.

2. Baud MG, et al. Science. 2014 Oct 31;346(6209):638-41.

GW 841819X (GW841819X)

生物&药学活性

物理化学性质&存储条件

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GW 841819X (GW841819X)

生物&药学活性

物理化学性质&存储条件

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