GW6471 | PPARα inhibitor | Probechem Biochemicals

Chemical Structure : GW6471

CAS No.: 880635-03-0

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GW6471 (GW-6471, GW 6471)

货号: PC-62872Not For Human Use, Lab Use Only.

GW6471 is a potent PPARα antagonist with IC50 of 0.24 uM, enhances the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR.

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10 mg	￥1880	In stock
25 mg	￥3280	In stock
50 mg	￥5280	In stock
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GW6471 is a potent PPARα antagonist with IC50 of 0.24 uM, enhances the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR.

物理化学性质&存储条件

分子量	619.685
分子式	C35H36F3N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((2S)-2-(((1Z)-1-Methyl-3-oxo-3-(4-(trifluoromethyl)phenyl)prop-1-enyl)amino)-3-(4-(2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy)phenyl)propyl)propanamide

参考文献

1. Müller MQ, et al. J Med Chem. 2009 May 14;52(9):2875-9.

2. Xu HE, et al. Nature. 2002 Feb 14;415(6873):813-7.

3. Muoio DM, et al. J Biol Chem. 2002 Jul 19;277(29):26089-97.

GW6471 (GW-6471, GW 6471)

生物&药学活性

物理化学性质&存储条件

参考文献

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GW6471 (GW-6471, GW 6471)

生物&药学活性

物理化学性质&存储条件

参考文献

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