GW 275175X |CAS:217950-62-4 Probechem Biochemicals

Chemical Structure : GW 275175X

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GW 275175X (GW275175X)

货号: PC-61947Not For Human Use, Lab Use Only.

GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.

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生物&药学活性

GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion.

物理化学性质&存储条件

分子量	398.034
分子式	C12H11BrCl2N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Bromo-5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

参考文献

1. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92.

2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51.

GW 275175X (GW275175X)

生物&药学活性

物理化学性质&存储条件

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GW 275175X (GW275175X)

生物&药学活性

物理化学性质&存储条件

参考文献

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