GSK_WRN2 | WRN helicase inhibitor | Probechem Biochemicals

Chemical Structure : GSK_WRN2

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货号: PC-22108Not For Human Use, Lab Use Only.

GSK_WRN2 is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 6.5, covalently targets WRN Cys727 residue.

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GSK_WRN2 is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 6.5, covalently targets WRN Cys727 residue.

分子量	309.33
分子式	C17H15N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(methylamino)-4-oxobut-2-yn-1-yl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carboxamide

1. Picco G, et al. Cancer Discov. 2024 Apr 9. doi: 10.1158/2159-8290.CD-24-0052.