GSK618069 | FXRP2 antagonist | Probechem Biochemicals

Chemical Structure : GSK618069

加入收藏

GSK618069 (GSK-618069)

货号: PC-22502Not For Human Use, Lab Use Only.

GSK618069 is a potent, selective antagonist of relaxin family peptide receptor 2 (RXFP2) with IC50 of 0.4 uM in HEK-hRXFP2 cAMP assays, 200-fold reduced potency against rRXFP2.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GSK618069 is a potent, selective antagonist of relaxin family peptide receptor 2 (RXFP2) with IC50 of 0.4 uM in HEK-hRXFP2 cAMP assays, 200-fold reduced potency against rRXFP2.
GSK618069 inhibits INSL3-stimulated CYP11B2 mRNA expression (IC50 = 2.8 µM) in adrenal cell assays.
GSK618069 reduces aldosterone and cortisol synthesis and release.

物理化学性质&存储条件

分子量	473.63
分子式	C27H35N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-cyclopentyl-4-(1-(piperidin-4-yl)-2-(pyridin-4-yl)-1H-benzo[d]imidazol-4-yl)piperazine-1-carboxamide

参考文献

1. Zhang SS, et al. Sci Rep. 2024 Jun 8;14(1):13209.

GSK618069 (GSK-618069)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GSK618069 (GSK-618069)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.