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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Estrogen Receptor/ERR-GSK4716
GSK4716

Chemical Structure : GSK4716

CAS No.: 101574-65-6

GSK4716 (GSK 4716)

货号: PC-20415Not For Human Use, Lab Use Only.

GSK4716 (GSK 4716) is a selective agonist of estrogen-related receptors ERRβ and ERRγ with EC50 of 1.3 uM (ERRγ).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GSK4716 (GSK 4716) is a selective agonist of estrogen-related receptors ERRβ and ERRγ with EC50 of 1.3 uM (ERRγ).
GSK4716 displays selectivity over ERRα and the classical estrogen receptors.

物理化学性质&存储条件

分子量 282.34
分子式 C17H18N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Hydroxybenzoic acid 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide

参考文献

1. Zuercher WJ, et al. J Med Chem. 2005 May 5;48(9):3107-9.

2. Krid H, et al. PLoS One. 2012;7(3):e34223.

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