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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-GSK4394835A
GSK4394835A

Chemical Structure : GSK4394835A

CAS No.: 3032458-06-0

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GSK4394835A (GSK4394835)

货号: PC-25896Not For Human Use, Lab Use Only.

GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A.

    物理化学性质&存储条件

    分子量 499.33
    分子式 C27H26BN3O6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3-(Benzyl(methyl)carbamoyl)-5-(4,7-dimethoxyquinoline-2-carboxamido)phenyl)boronic Acid

    参考文献

    1. Eaton SA, et al. J Med Chem. 2025 Dec 2. doi: 10.1021/acs.jmedchem.5c03081.

    2. Rowley AM, et al. J Med Chem. 2024 Feb 8;67(3):2049-2065.

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