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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-GSK-3-GSK3β inhibitor MJ34
GSK3β inhibitor MJ34

Chemical Structure : GSK3β inhibitor MJ34

CAS No.: 2099015-13-9

GSK3β inhibitor MJ34 (ISO-1479)

货号: PC-22537Not For Human Use, Lab Use Only.

GSK3β inhibitor MJ34 (ISO-1479) is a potent, GSK3β selective inhibitor with IC50 of 15.4 nM, significantly reduces growth and survival of human mutant KRas dependent pancreatic tumors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GSK3β inhibitor MJ34 (ISO-1479) is a potent, GSK3β selective inhibitor with IC50 of 15.4 nM, significantly reduces growth and survival of human mutant KRas dependent pancreatic tumors.

物理化学性质&存储条件

分子量 315.38
分子式 C19H17N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(5-(2-ethylphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

参考文献

1. Ayaz MO, et al. Life Sci. 2024 Aug 15;351:122840.

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