GSK3β-IN-1a (GSK-3β inhibitor 8) |CAS:1139875-74-3 Probechem Biochemicals

Chemical Structure : GSK3β-IN-1a

CAS No.: 1139875-74-3

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GSK3β-IN-1a (GSK-3β inhibitor 8)

货号: PC-62069Not For Human Use, Lab Use Only.

GSK3β-IN-1a (GSK-3β inhibitor 8) is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM.

规格	价格	库存
5 mg	￥1980	In stock
10 mg	￥2980	In stock
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100 mg		Get quote

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生物&药学活性

GSK3β-IN-1a (GSK-3β inhibitor 8) is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM.
GSK3β-IN-1a (GSK-3β inhibitor 8) induces replication of growth-arrested R7T1 β cells in a dose-dependent manner with EC50 of 1.1 uM, likely mediates β-cell proliferation through the Wnt signaling pathway.

物理化学性质&存储条件

分子量	413.924
分子式	C20H20ClN5OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-chloro-4-((4-(thiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone

参考文献

1. Wang W, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1427-32.

GSK3β-IN-1a (GSK-3β inhibitor 8)

生物&药学活性

物理化学性质&存储条件

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GSK3β-IN-1a (GSK-3β inhibitor 8)

生物&药学活性

物理化学性质&存储条件

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