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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-GSK-3-GSK3 inhibitor 117
GSK3 inhibitor 117

Chemical Structure : GSK3 inhibitor 117

CAS No.: 1908431-17-3

GSK3 inhibitor 117

货号: PC-20191Not For Human Use, Lab Use Only.

GSK3 inhibitor 117 is a novel selective GSK-3 inhibitor, shows cytotoxicity against AML in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GSK3 inhibitor 117 is a novel selective GSK-3 inhibitor, shows cytotoxicity against AML in vitro and in vivo.

    物理化学性质&存储条件

    分子量 444.85
    分子式 C18H13ClN6O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-Chloro-N-[4-[5-[[[5-(1-oxido-4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]methyl]-1,2,4-oxadiazol-3-yl]phenyl]acetamide

    参考文献

    1. Patent WO2016061344 A1.

    2. Reshmi Parameswaran, et al. Nat Commun. 2016 Apr 4;7:11154.

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