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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Liver X Receptor (LXR)-GSK3987
GSK3987

Chemical Structure : GSK3987

CAS No.: 264206-85-1

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GSK3987 (GSK 3987)

货号: PC-38574Not For Human Use, Lab Use Only.

GSK3987 is a potent liver X receptor (LXR) agonist with EC50 of 50 nM and 40 nM for LXRα and LXRβ, respectively.

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5 mg ￥2280 In stock
10 mg ￥3780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GSK3987 is a potent liver X receptor (LXR) agonist with EC50 of 50 nM and 40 nM for LXRα and LXRβ, respectively.
GSK3987recruits the steroid receptor coactivator-1 to human LXRα and LXRβ with EC50 of 40 nM in functional assays.

物理化学性质&存储条件

分子量 384.435
分子式 C24H20N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Benzyl-3-(4-methoxyanilino)-4-phenylpyrrole-2,5-dione

参考文献

1. Jaye MC, et al. J Med Chem. 2005 Aug 25;48(17):5419-22.

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