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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Kynurenine 3-Monooxygenase (KMO)-GSK366
GSK366

Chemical Structure : GSK366

CAS No.: 1953157-39-5

GSK366 (GSK-366, GSK 366)

货号: PC-61184Not For Human Use, Lab Use Only.

GSK366 is a novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GSK366 is a novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.

物理化学性质&存储条件

分子量 361.782
分子式 C17H16ClN3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-(5-chloro-6-(1-(6-methylpyridazin-3-yl)ethoxy)benzo[d]isoxazol-3-yl)propanoic acid

参考文献

1. Hutchinson JP, et al. Nat Commun. 2017 Jun 12;8:15827.

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