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首页-小分子抑制剂&激动剂-Epigenetics-DNA Methyltransferase (DNMT)-GSK3543105
GSK3543105

Chemical Structure : GSK3543105

CAS No.: 2170139-57-6

GSK3543105 (GSK 3543105)

货号: PC-73377Not For Human Use, Lab Use Only.

GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM.

    物理化学性质&存储条件

    分子量 464.588
    分子式 C24H28N6O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((3,5-dicyano-4-ethyl-6-(4-(2-hydroxyethyl)-1,4-diazepan-1-yl)pyridin-2-yl)thio)-2-phenylacetamide

    参考文献

    1. Horton JR, et al. Structure. 2022 Mar 28:S0969-2126(22)00090-9.

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