GSK3491943 | TRPV4 inhibitor | Probechem Biochemicals

Chemical Structure : GSK3491943

加入收藏

货号: PC-22742Not For Human Use, Lab Use Only.

GSK3491943 is a potent, selective TRPV4 inhibitor with IC50 of 3.2 nM (hTRPV4).

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GSK3491943 is a potent, selective TRPV4 inhibitor with IC50 of 3.2 nM (hTRPV4).

分子量	491.35
分子式	C18H16Cl2N2O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Chloro-4-(((3R,4S)-4-((4-chlorophenyl)sulfonyl)-3-hydroxy-3-(hydroxymethyl)pyrrolidin-1-yl)sulfonyl)benzonitrile

1. Joseph E Pero, et al. J Med Chem. 2018 Dec 27;61(24):11209-11220.

2. Carl A Brooks, et al. J Med Chem. 2019 Oct 24;62(20):9270-9280.