GSK3326595 | PRMT5 inhibitor | Probechem Biochemicals

Chemical Structure : GSK3326595

CAS No.: 1616392-22-3

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货号: PC-42405Not For Human Use, Lab Use Only.

Pemrametostat (GSK3326595, EPZ015938) is a potent, selective, reversible and orally active PRMT5 inhibitor with IC50 of 22 nM.

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Pemrametostat (GSK3326595, EPZ015938) is a potent, selective, reversible and orally active PRMT5 inhibitor with IC50 of 22 nM.

分子量	452.54928
分子式	C24H32N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	4-Pyrimidinecarboxamide, 6-[(1-acetyl-4-piperidinyl)amino]-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-

1. Drew Rasco, et al. Abstract CT038, AACR. DOI: 10.1158/1538-7445.

2. Patent WO 2016022605 A1, Formula A.