Chemical Structure : GSK2795039
CAS No.: 1415925-18-6
货号: PC-45569Not For Human Use, Lab Use Only.
GSK2795039 (GSK 2795039) is a potent and selective inhibitor of NOX2 (NADPH oxidase 2) with pIC50 of 6.57.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1880 | In stock | |
10 mg | ¥2980 | In stock | |
25 mg | ¥4980 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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GSK2795039 (GSK 2795039) is a potent and selective inhibitor of NOX2 (NADPH oxidase 2) with pIC50 of 6.57.
GSK-2795039 exhibits good selectivity for NOX2 over other NOX isoforms, xanthine oxidase and eNOS.
GSK-2795039 abolishes the production of ROS by activated NOX2 enzyme in a paw inflammation model of acute pancreatitis.
分子量 | 450.5565 | |
分子式 | C23H26N6O2S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
DMSO: ≥ 32 mg/mL |
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Chemical Name/SMILES |
1H-Pyrazole-3-sulfonamide, N-[3-(2,3-dihydro-1-methyl-1H-indol-6-yl)-1-(1-methylethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl- |
1. Hirano K, et al. Antioxid Redox Signal. 2015 Aug 10;23(5):358-74.
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