欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-PERK-GSK2606414
GSK2606414

Chemical Structure : GSK2606414

CAS No.: 1337531-36-8

加入收藏

GSK2606414 (GSK 2606414, GSK-2606414)

货号: PC-45410Not For Human Use, Lab Use Only.

GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM.

规格 价格 库存 数量
5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
50 mg ￥4280 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM.
GSK2606414 inhibits PERK activation in cells and inhibits the growth of human tumor xenograft in mice.
GSK2606414 reduces p-eIF2α levels and enhanced novel taste learning and conditioned taste aversion, but not memory retrieval in rats.

物理化学性质&存储条件

分子量 451.4437
分子式 C24H20F3N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 31 mg/mL
Chemical Name/SMILES

Ethanone, 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]-

参考文献

1. Axten JM, et al. J Med Chem. 2012 Aug 23;55(16):7193-207.

2. Ounallah-Saad H, et al. J Neurosci. 2014 Oct 29;34(44):14624-32.

3. Guthrie LN, et al. J Biol Chem. 2016 Jul 22;291(30):15830-40.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: