欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-GSK2239633A
GSK2239633A

Chemical Structure : GSK2239633A

CAS No.: 1240516-71-5

加入收藏

GSK2239633A (GSK2239633)

货号: PC-73262Not For Human Use, Lab Use Only.

GSK2239633A is a potent, allosteric CC-chemokine receptor 4 (CCR4) antagonist with pIC50 of 7.83 in 35S-GTPγS competition assay.

规格 价格 库存 数量
5 mg ￥1380 In stock
10 mg ￥2180 In stock
25 mg ￥3780 In stock
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GSK2239633A is a potent, allosteric CC-chemokine receptor 4 (CCR4) antagonist with pIC50 of 7.83 in 35S-GTPγS competition assay.
GSK2239633A binds to CCR4 at an intracellular allosteric site denoted site II. GSK2239633A inhibits thymus activation-regulated chemokine (TARC) -induced F-actin polymerization in human whole blood.

物理化学性质&存储条件

分子量 549.06
分子式 C24H25ClN4O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-((3-((5-chlorothiophene)-2-sulfonamido)-4-methoxy-1H-indazol-1-yl)methyl)benzyl)-2-hydroxy-2-methylpropanamide

参考文献

1. Procopiou PA, et al. J Med Chem. 2013 Mar 14;56(5):1946-60.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: