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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-P2X Receptor-GSK1482160
GSK1482160

Chemical Structure : GSK1482160

CAS No.: 1001389-72-5

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GSK1482160 (GSK-1482160)

货号: PC-22645Not For Human Use, Lab Use Only.

GSK1482160 is an orally available allosteric P2X7 receptor negative allosteric modulator (NAM) with pIC50 of 8.5 and 6.5 for human and rat P2X7R respectively.

规格 价格 库存 数量
10 mg ￥1380 In stock
25 mg ￥2480 In stock
50 mg ￥3980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GSK1482160 is an orally available allosteric P2X7 receptor negative allosteric modulator (NAM) with pIC50 of 8.5 and 6.5 for human and rat P2X7R respectively.

物理化学性质&存储条件

分子量 334.72
分子式 C14H14ClF3N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1-methyl-5-oxo-L-prolinamide

参考文献

1. Ali Z, et al. Br J Clin Pharmacol. 2013 Jan;75(1):197-207.

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