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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-GSK-812
GSK-812

Chemical Structure : GSK-812

CAS No.: 630407-66-8

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GSK-812 (GSK812)

货号: PC-61812Not For Human Use, Lab Use Only.

GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors.

    物理化学性质&存储条件

    分子量 471.996
    分子式 C25H26ClNO4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-[4-(4-chloro-benzyloxy)-benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

    参考文献

    1. Baranov P, et al. J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422.

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