GSK-575594A |CAS:909418-68-4 Probechem Biochemicals

Chemical Structure : GSK-575594A

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GSK-575594A (GSK575594A)

货号: PC-63115Not For Human Use, Lab Use Only.

GSK-575594A is a potent, selective GPR55 agonist with pEC50 of 6.8 at GPR55 in yeast assay, displays 60-fold selective for GPR55 over GlyT1 (pIC50=5.0).

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生物&药学活性

GSK-575594A is a potent, selective GPR55 agonist with pEC50 of 6.8 at GPR55 in yeast assay, displays 60-fold selective for GPR55 over GlyT1 (pIC50=5.0).
GSK-575594A activates human GPR55 but not rodent GPR55, and is inactive at cannabinoid receptors.

物理化学性质&存储条件

分子量	471.523
分子式	C24H23F2N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[4-(4-amino-2-fluorophenyl)piperazin-1-yl]-[2-(4-fluorophenyl)-5-methylsulfonylphenyl]methanone

参考文献

1. Brown AJ, et al. J Pharmacol Exp Ther. 2011 Apr;337(1):236-46.

GSK-575594A (GSK575594A)

生物&药学活性

物理化学性质&存储条件

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GSK-575594A (GSK575594A)

生物&药学活性

物理化学性质&存储条件

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